Cissus quadrangularis (CQ), also called the Veldt grape, the Devil’s backbone, or asthisamhari, is indigenous to parts of Africa and India. It has been utilized for centuries as aconventional medicine like Ayurveda and Siddha. It is now widely acknowledged in the nutritional supplement industry for its health advantages, particularly bone health, weight control, and joint pain relief. The nature of CQ, the science underlying its health advantages, the ideal dosage, potential interactions, and responsible use of this plant-based supplement are all covered in this article.
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Cissus Quadrangularis: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information is an original (NootropicsPlanet) article.
Nature of Cissus Quadrangularis
CQ is a member of the grape family. It is known for its succulent nature and four-sided stem sections, and it adapts well to dry environments. CQ’s extensive phytochemical makeup, which includes substances like flavonoids, triterpenoids, and steroids, is what gives it its medicinal benefits.
The chemical compounds in CQ is what gives it its pharmacological properties. Polyphenolic substances called flavonoids are highly effective anti-inflammatory, antioxidant, and anticancer agents. Triterpenoids, on the other hand, have potent antiviral, immunomodulatory, and antimicrobial properties. The CQ steroid -Sitosterol is linked to anti-diabetic, anti-inflammatory, and cholesterol-lowering properties.
Health Benefits
CQ‘s contribution to bone health is one of its main advantages, making it a potential all-natural treatment for ailments like osteoporosis and fracture healing. Its flavonoids, which prevent osteoclastogenesis, and the process of bone cell breakdown, are crucial. These factors promote a balanced relationship between bone formation and resorption. Additionally, CQ’s benefits for bone health include high calcium content and the ability to stimulate osteoblasts, cells that aid in bone formation.
Joint Health and Weight Loss
CQ can help with weight management, especially with lowering body fat percentage. According to research, it reduces the absorption of fat by inhibiting the lipase enzyme. The plant’s analgesic and anti-inflammatory properties are advantageous for joint health. CQ can treat conditions like osteoarthritis by controlling inflammatory cytokines and pain mediators.
Chemistry of Cissus Quadrangularis
Cissus quadrangularis (CQ) has a high phytochemical makeup, which is a complex mixture of bioactive substances like flavonoids, triterpenoids, phytosterols, and -Sitosterol. All of these substances are largely responsible for their therapeutic potential.
Flavonoids are polyphenolic compounds and are known for their anti-inflammatory, anti-oxidant, and anticancer properties. They are believed to have therapeutic potential for treating a variety of diseases by modulating several cellular processes. This occurs by preventing or promoting interactions between enzymes or receptors.
Triterpenoids, a different class of compounds found in CQ, have potent antiviral, immunomodulatory, and antimicrobial properties. Triterpenoids exert their biological effects through a variety of mechanisms that interact with a variety of cellular targets.
Another important component of CQ is -sitosterol, a steroid derived from plants. Due to its structural resemblance to cholesterol and its ability to prevent cholesterol absorption in our intestines, it is linked to anti-diabetic, anti-inflammatory, and cholesterol-lowering properties.
Physiological Properties of CQ
CQ promotes bone health by interacting with the processes of bone remodeling. The flavonoids in CQ prevent osteoclastogenesis, a process that destroys bone cells, which preserves a healthy balance between bone formation and resorption. CQ’s advantages for bone health also result from its ability to stimulate osteoblasts, which are the cells that aid in bone formation.
Weight Control
CQ helps with weight control by affecting lipid metabolism. It functions by preventing the activity of the lipase enzyme, which reduces the absorption of fat. By preventing the digestion and absorption of fat, our calorie intake is reduced, which is what aids in weight management.
Joint Wellness
The joint health benefits of CQ’s anti-inflammatory and analgesic properties are substantial. Its active ingredients control pain and inflammation mediators, which is helpful for treating conditions like osteoarthritis.
In conclusion, CQ’s health advantages result from its intricate interactions with a range of physiological processes. Its effects on lipid digestion and absorption, inflammation modulation, and bone cell metabolism make it a versatile plant-based supplement with a variety of health benefits. However, more research may be required to fully understand the complex abilitiesand long-term security of CQ.
Optimal Dosage
The amount of CQ to take depends on a variety of factors, including your age, health status, and desired health effects. In clinical studies, daily doses of 300 to 600 mg are frequently used. To determine what dosage recommendations you should follow, more research is necessary. Before beginning CQ supplementation, as with any supplement, you need to speak with your healthcare professional to establish the appropriate dose.
Cissus Quadrangularis: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information is the (NootropicsPlanet) report.
Side Effects
Although CQ is regarded as safe, some side effects, such as gastrointestinal discomfort, headaches, and dry mouth, are common. Due to a lack of safety information on these potential side effects, we advise women that are pregnant and/or nursing to avoid CQ.
Potential Substance Interactions
Drug interactions involving CQ are possible. Given its potential to lower blood sugar levels, it enhances the effects of diabetic medications, which can cause hypoglycemia. This is similar to how antihypertensive medications can have additive effects when combined with their blood pressure-lowering properties. When you are considering CQ supplementation, it is crucial to let your healthcare provider know about any medications you are taking.
Responsible Use of Cissus Quadrangularis
Following dosage recommendations, understanding potential side effects, and being aware of any drug interactions are all necessary for responsible use of CQ. Although CQ has a long history of traditional use, it should not be used in place of standard medical care. We strongly advise that CQ be incorporated into your healthcare routine with the help of your healthcare professional.
Cissus Quadrangularis:
Conclusion
Cissus quadrangularis is extremely beneficial if you are looking for a supplement that supports bone health, helps with weight management, and improves joint health. To fully understand its long-term safety, efficacy, ideal dosage, and potential interactions, more research is still required. CQ is a promising candidate as we transition to using plant-based remedies and adding dietary supplements to our daily routines, highlighting the significance of incorporating this traditional usage of CQ.
References:
- Antioxidant and anti-inflammatory properties of flavonoids. Retrieved From: https://pubmed.ncbi.nlm.nih.gov/29662438/
- Role of β-sitosterol in ameliorating high fat diet induced changes in lipid metabolism in mice. Retrieved From: https://www.nature.com/articles/s41598-018-36453-6
- Cissus quadrangularis: Pharmacological uses and effects. Retrieved From: https://onlinelibrary.wiley.com/doi/full/10.1111/1541-4337.12418
Important Note: The information contained in this article (Cissus Quadrangularis: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information) is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.
Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.
