Wood Sorrel: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information


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Over 800 different species of the perennial herbaceous plant known as wood sorrel (Oxalis spp.) have been identified from all over the world. It belongs to the Oxalidaceae family and is distinguished by its clover-like look, tiny yellow flowers, and tart, lemon-like flavor. The plant has a long history of use in both medicine and cuisine, with its roots and blooms being traditionally used for their curative powers while its leaves and stems are eaten as food. This article explores the phytochemistry, health advantages, recommended dosage, negative effects, possible drug interactions, and ethical usage of wood sorrel as a dietary supplement.

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Wood Sorrel: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information is an original (NootropicsPlanet) article.

Nature of Wood Sorrel

The family Oxalidaceae includes a genus of perennial herbaceous plants known as wood sorrel, or Oxalis. The trifoliate, clover-like leaves, tiny yellow or white blooms, and tart, lemon-like flavor of the plants set them apart from other plants. Hardy in nature, wood sorrel may thrive in a variety of settings, including woodlands, meadows, and even cities.

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Over 800 different species of wood sorrel exist in the world, with Oxalis acetosella, Oxalis stricta, and Oxalis corniculata being some of the most widespread varieties. Depending on the type and locale, the plant goes by a variety of names, including common wood sorrel, creeping wood sorrel, and yellow wood sorrel. Wood sorrel has a long history of use in both medicine and cuisine, with its roots and blossoms being used for therapeutic purposes while its leaves and stems are eaten as food.

Health Benefits of Wood Sorrel

The flavonoids and phenolic acids in wood sorrel gives the plant its beneficial qualities. Free radicals are unstable molecules that can cause oxidative stress, cellular damage, and a higher chance of developing chronic diseases like cancer, heart disease, and neurological disorders. These substances have the ability to neutralize free radicals. By lowering oxidative stress and inflammation, wood sorrel’s antioxidant properties may be able to help people avoid developing these conditions.

It has been demonstrated that the flavonoids and phenolic acids in wood sorrel have anti-inflammatory properties by blocking the activity of pro-inflammatory cytokines and enzymes including cyclooxygenase-2 (COX-2) and lipoxygenase. This may lessen the symptoms of inflammatory diseases such as inflammatory bowel disease, asthma, and arthritis.

Staphylococcus aureus, Escherichia coli, and Salmonella typhimurium have all been shown to be resistant to the antibacterial properties of wood sorrel. Wood sorrel’s flavonoids and phenolic acids, which can stop bacterial development and alter their cellular structure, are principally responsible for its antibacterial effects.

Heart disease.

Chemistry of Wood Sorrel

The phytochemicals flavonoids, phenolic acids, and organic acids are abundant in wood sorrel. The main organic acid in the plant is oxalic acid, which gives it its acidic flavor and has been extensively studied because of its possible health effects. Quercetin, kaempferol, and chlorogenic acid are important phytochemicals also found in wood sorrel, and they all have biological properties such as antioxidant, anti-inflammatory, and antibacterial actions.

Physiological Mechanism of Action

Through various mechanisms of action in the body, the various phytochemicals found in wood sorrel contribute to its wide range of health advantages. The following are some of the main mechanisms of action:

1. Antioxidant qualities: Wood sorrel contains flavonoids and phenolic acids that can scavenge free radicals and lessen oxidative stress, preserving cells from deterioration. They can also chelate metal ions, which can increase oxidative stress and produce reactive oxygen species (ROS).

2. Anti-inflammatory properties: The flavonoids and phenolic acids in wood sorrel can control the production of cytokines, chemokines, and adhesion molecules, which are pro-inflammatory mediators. Additionally, they have the ability to block the activity of inflammatory enzymes like COX-2, lipoxygenase, and inducible nitric oxide synthase (iNOS).

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3. Antimicrobial activity: The antimicrobial properties of wood sorrel are primarily attributed to its flavonoids and phenolic acids, which can interfere with bacterial quorum sensing, disrupt bacterial cell wall and membrane integrity, and inhibit the synthesis of bacterial proteins.

4. Diuretic effects: Wood sorrel has been shown to have diuretic effects, which encourage the body to expel water and electrolytes. This can assist in maintaining a healthy fluid balance and renal function.

5. Oxalic acid metabolism: In people who are sensitive, the high oxalic acid concentration of wood sorrel promotes the production of calcium oxalate crystals, which can result in kidney stones. This occurs physiologically when oxalic acid binds to calcium ions to generate insoluble calcium oxalate crystals that can build up in the kidneys.

Structure of Kidney.

Optimal Dosage of Wood Sorrel

The best amount of wood sorrel to take as a nutritional supplement will vary depending on the user’s age, weight, and general health. It is difficult to develop a standardized dosage for wood sorrel because there is a dearth of scientific study on the exact dosage for this herb. As a general rule, it is advised to begin with a modest dosage and gradually raise it while keeping an eye out for any negative effects. To ensure the safe and efficient usage of wood sorrel supplements, speaking with a healthcare practitioner before beginning is advised.

Side Effects of Wood Sorrel

When consumed in moderation, wood sorrel is typically regarded as safe to eat. However, due to the high oxalic acid content in the plant, excessive consumption of wood sorrel may cause the development of calcium oxalate stones, especially in people who already have kidney disorders or a history of kidney stones. Additionally, after consuming wood sorrel, some people may experience gastrointestinal symptoms like nausea, diarrhea, and abdominal cramping.

Young girl feeling vomit.

Potential Substance Interactions with Wood Sorrel

Some medications, especially those that have an impact on the kidneys or affect how calcium and oxalate are metabolized, may interact with wood sorrel. Medication interactions with wood sorrel include, for instance:

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1. Diuretics: The diuretic characteristics of wood sorrel may enhance the effects of diuretic drugs, increasing the risk of electrolyte imbalances and dehydration. Before combining wood sorrel with diuretic medications, it is imperative to speak with a medical professional.

2. Calcium supplements: Due to the high levels of oxalic acid in wood sorrel, these supplements may not be as effective because of possible interference with calcium absorption. To reduce any potential interactions, it is best to work with a healthcare provider to identify the right timing and dosage of wood sorrel if you take calcium supplements.

3. Anticoagulants: Quercetin and kaempferol, two flavonoids found in wood sorrel, may interact with anticoagulants like warfarin to change how well they work. Before taking wood sorrel as a dietary supplement, people who are taking anticoagulant therapy should speak with a medical expert.

Responsible Uses of Wood Sorrel

 Due to the paucity of scientific studies on the ideal dosage of wood sorrel, it is advised to begin with a low dosage and gradually raise it while keeping an eye out for any negative effects. People should speak with a healthcare provider before beginning wood sorrel supplementation, particularly if they have pre-existing medical issues, are pregnant or nursing, or are taking drugs that may interact with wood sorrel.

While wood sorrel has many health advantages, consuming too much of it can have negative effects like kidney stone formation or gastrointestinal discomfort. It’s crucial to consume wood sorrel sparingly and in accordance with dose recommendations. To guarantee the highest level of quality and security for wood sorrel supplements, it’s essential to get goods from reliable vendors who follow proper production procedures and offer independent testing for impurities and potency.

Wood Sorrel:


Inflammation is a common health concern that many people across the globe suffer from, causing them to look to holistic health remedies for a natural form of relief. Whether you’re looking to get rid of internal inflammation, or if you’d like to lessen excessive redness and sensitivity externally, you can take wood sorrel to guide you toward the results you’re looking for. Wood sorrel is not always the most common option, but it can work well for those without kidney issues or low calcium levels that require supplementation.

Consider wood sorrel as an addition to a healthy balanced diet. If you are prone to kidney stones, you should avoid consuming wood sorrel, as it may make this issue worse.

Lady having supplement.


  1. Antioxidant properties of wood sorrel (Oxalis spp.) and its potential health benefits. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212925/
  2. Flavonoids and phenolic acids in wood sorrel: A comprehensive review. Retrieved from: https://www.frontiersin.org/articles/10.3389/fphar.2018.01456/full
  3. The role of oxalic acid in kidney stone formation and potential health risks associated with wood sorrel consumption. Retrieved from: https://www.ajkd.org/article/S0272-6386(17)30863-6/fulltext
  4. Wood sorrel: A traditional medicinal plant with potential health benefits and its modern applications. Retrieved from: https://www.mdpi.com/2076-3921/9/9/802

Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.

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