Eurycoma Longifolia: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information


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Southeast Asian native eurycoma longifolia, also known as tongkat ali or Malaysian ginseng, is a flowering plant of the simaroubaceae family. Many researchers have looked into the effectiveness of the plant’s roots as a health supplement in recent years due to its possible therapeutic effects. This article provides a thorough description of eurycoma longifolia, including its benefits for health, recommended dose, side effects, and possible drug interactions. It also covers the  details of the chemical and physiological processes that underlie its impact on the body and brain.

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Eurycoma Longifolia: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information is an original (NootropicsPlanet) article.

Nature of Eurycoma Longifolia

In Southeast Asian nations, especially Malaysia and Indonesia, eurycoma longifolia is a tall, thin, evergreen shrub tree that is rather prevalent. Its roots are notorious for having a bitter taste and have been used in traditional medicine for many years to cure various  conditions, including bacterial infections, fever, and erectile dysfunction.

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Health Benefits of Eurycoma Longifolia

The numerous benefits of tongkat ali are  attributed  to its abundance of bioactive substances, such as alkaloids, saponins, and quassinoids.

  1. Men’s health: Eurycoma longifolia can greatly  improve men’s  sexual health.   It can encourage the synthesis of testosterone, which can boost libido, enhance sperm quality, and stimulate muscular building.
  1. Energy and Mood Enhancer: Research suggests that eurycoma longifolia can lessen tiredness and increase stamina. It can also improve your  mood and lower levels of stress, presumably as a result of how it affects hormone control.
  1. Antimicrobial Properties: Eurycoma longifolia has antimicrobial properties against several bacteria and yeasts, which suggest that it can be effectively treat illnesses.
Men's health.

Chemistry of Eurycoma longifolia

Eurycoma longifolia has many bioactive components, including quassinoids, saponins, eurycomanone, and different alkaloids  that are responsible for its medicinal properties.  The quassinoid eurycomanone is  a significant contributor to the plant’s health benefits. The hypothalamic-pituitary-adrenal axis and the hypothalamic-pituitary-gonadal axis  are  affected by the eurycomanone’s effects on hormone balance in the body.

Physiological Properties  of Eurycoma Longifolia

Numerous intriguing theories have been put out in an effort to better understand the physiological mechanisms underlying eurycoma longifolia’s effects.

  1. Hormone Regulation: By triggering the release of luteinizing hormone, which instructs the leydig cells in the testes to generate testosterone, eurycomanone and other active substances can increase testosterone synthesis.
  1. Energy and Mood:  This effect is  related to how cortisol levels are affected. Eurycoma longifolia can control stress levels and enhance your mood and energy by potentially lowering cortisol, a hormone associated with stress.
  1. Antimicrobial Properties: The plant’s many bioactive substances that directly prevent microbial development are responsible for its  antimicrobial properties.

Optimal Dosage of Eurycoma longifolia

The ideal dose of eurycoma longifolia is based on a number of variables, including your age, general health, and the ailments being treated. A typical dosage for supplements is 200–300 mg daily, however, medical professionals usually suggest  using a different amount. Before beginning a new regimen, it is wise to speak with your healthcare professional.

Side Effects of Eurycoma longifolia

Although it is usually  safe to consume, some people can encounter minor side effects like sleeplessness, restlessness, or mild stomach pain. Long-term high doses can also have an impact on liver health. Therefore, if you have a  liver disorder or are  taking drugs that damage the liver, you should use caution and talk to your doctor.

Man looking sad.

Potential Substance Interactions with Eurycoma Longifolia

Eurycoma longifolia can interact with hormone treatments or drugs that regulate hormone levels due to its tendency to modify hormone levels, especially  testosterone. As a result, before taking tongkat ali, if you are  receiving hormone-related therapy, you  should speak with your doctor before using it.

Best Use of Eurycoma Longifolia

Effective and secure use of eurycoma longifolia necessitates a balanced strategy that requires you to take into consideration a number of factors:

  1. Dosage: Eurycoma longifolia is often used as a dietary supplement in the form of a  powder that dissolves in water or can also be taken in the form of  capsules. A typical dosage is between 200 and 300 mg daily, however, this can vary based on your specific health status, and the particular product. Always follow the dosing instructions given by your doctor or the product’s manufacturer.
  1. Consistency: Daily, consistent use is typically advised to acquire its benefits fully, particularly when taking it to raise testosterone levels or improve your mood.
  1. Timing: It is advised  to take eurycoma longifolia in the morning or before physical activity due to  its conceivable benefits on raising energy levels. It can be disruptive if you take it at night.
  1. Caution: Before using eurycoma longifolia, if you have any  liver problems, diseases connected to hormones, or  are taking drugs that alter hormones, you should speak with a doctor before use.
  1. Storage: Eurycoma longifolia should be kept out of the reach of children and preserved in a cool, dry location, away from direct sunlight.

Eurycoma Longifolia:


Eurycoma longifolia is a highly beneficial natural herb supplement that can help improve overall health and way of life, especially for men. If you are struggling with disorders such as erectile dysfunction, mood, and energy balance, or even diabetes, eurycoma longifolia may be the right supplement for you. This herb can also increase testosterone levels in general, which can improve mood, sperm count, and sexual libido. Keep in mind that if you have any liver disorders, you should first ask your doctor if it is safe for you to take because this herb can cause side effects such as fatty liver disease, jaundice, or cirrhosis.

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Sperm cells.


  1. “Eurycoma Longifolia as a potential adoptogen of male sexual health.” Retrieved From:
  2. “Eurycoma longifolia: Medicinal Plant in the Prevention and Treatment of Male Osteoporosis due to Androgen Deficiency.” Retrieved From:
  3. “Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men.” Retrieved From:
  4. “Effects of Eurycoma longifolia on Testosterone Level and Bone Structure in an Aged Orchidectomised Rat Model.” Retrieved From:

Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.

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