Finding the Best Supplements for Brain Fog After COVID: 5 Top Brands Reviewed

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Post-COVID brain fog is a growing concern among people of all ages, and certain natural supplements show promise for relief.  We’ll count down five top brands in our search for the best supplements for brain fog after COVID.

COVID-19’s effects on your respiratory system are well-known, but its neurological symptoms are equally concerning. COVID attacks the brain in many ways, notably starving the brain of oxygen and even causing encephalitis. Inflammation of the brain is especially dangerous, as it can cause the brain to alter the way it signals, and may cause symptoms such as confusion, difficulty concentrating, memory problems, and even depression.

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The Best Supplements for Memory and Brain Fog: 5 Top Brands Reviewed

This “brain fog”— sluggish, fuzzy, clouded thinking — is exaggerated in those suffering from long spells of COVID and is perhaps chief among the devastating lingering neurological symptoms they experience. A 2022 study reported that approximately 68% of patients experienced memory impairment. Below we’ll list five of the most effective natural supplements to help alleviate post-COVID brain fog. Read on to discover some quality supplements that may help restore your cognitive function.

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Finding the Best Supplements for Brain Fog After COVID: 5 Top Brands Reviewed is an original (NootropicsPlanet) article.

Supplements for brain fog after COVID:

5. Olly’s Brain Softgels

Olly’s Brain Softgels are designed to support and maintain overall brain health while improving mental sharpness. They include several ingredients with promising neural benefits: Bacopa extract has promising effects on memory enhancement, learning, and focus; omega-3, an essential fatty acid, helps improve your overall cognitive performance; and vitamins B6 and B12 are linked with developing and preserving healthy brain function. Olly’s Brain Softgels also include a blueberry flavor extract, which, apart from delivering a delicious taste, contains antioxidants and anthocyanins. The former helps protect against the damaging effects of free radicals, while the latter may help protect against neurodegenerative disorders.

Woman holding Brain supplements for brain fog after covid

Supplements for brain fog after COVID:

4. Confidence

Confidence’s main active ingredient is DHH-B, which is a natural derivative of magnolia-tree bark. It is traditionally used in Chinese medicine as a stress and anxiety manager due to its ability to reduce cortisol levels in the brain and improve mood. Recent research has demonstrated its neuroprotective properties in combating oxidative stress. Confidence also includes other mood-boosting ingredients, including sage, which improves GABA neurotransmission and its calming effects, and Saffron, which improves serotonin levels. With all this in mind, Confidence is an effective mood elevator that helps “promote a calm, relaxed state of mind,” and increased alertness and focus. 

Supplements for brain fog after COVID:

3. Elysium’s Matter

Elysium’s Matter helps combat brain aging with a novel tri-vitamin complex developed by the University of Oxford. It includes an assortment of cognitively beneficial ingredients, including bountiful levels of B vitamins and the omega-3 fatty acids EPA and DHA, which have been demonstrated through research to have anti-inflammatory and neuroprotective properties and are good for memory enhancement. Furthermore, Matter includes antioxidant bilberry anthocyanins, which can help combat oxidative stress. Overall, this diverse list of ingredients is designed to not only help combat aging but also to support holistic brain health, creating a system for improving brain function and maintenance over time.

Omega 3 supplements

Supplements for brain fog after COVID:

2. Moon Juice: Brain Dust

Tapping into the vibrant benefits of adaptogens, Moon Juice’s Brain Dust helps induce mental alertness, concentration, and stamina. Moon Juice includes a blend of natural, cognitive-boosting supplements, including the mushroom Lion’s Mane, the herbs ginko and ashwagandha, and the root Rhodiola. Lion’s Mane is particularly promising in its effects on cognitive function, as research has found that it contains considerable amounts of vitamin B12, which is crucial to the development and function of brain and nerve cells, and, consequently, overall cognitive function. 

Supplements for brain fog after COVID:

1. Medicine Man Plant Co’s The Brain Pill

While those looking to improve and maintain cognitive function while combating the effects of brain fog can’t go wrong with any of the above-mentioned cognitive supplements, the only supplement that combines ethnobotany and chemistry to aid the brain’s natural processes is Medicine Man Plant Co’s The Brain Pill. Crafted from a natural herbal formula that utilizes the cognitive-enhancing properties of plants and mushrooms, Medicine Man’s The Brain Pill contains the main active ingredients of Lion’s Mane mushroom, ginkgo, and sage.


Lion’s Mane, for example, has been widely studied for its neurotrophic factors, which are important in promoting the growth and plasticity of neurons in the brain. It’s notably been found to contain hericenones and erinacines, key compounds in Nerve Growth Factor (NGF). This is the most significant neurotrophic process and is essential to the growth, maintenance, and survival of the brain. Likewise, Sage contains rosmarinic acid, which helps increase Brain-Derived Neurotrophic Factor (BDNF) levels in the brain. BDNF is a vital compound that plays a large role in neuronal growth and survival, as well as general functioning. In fact, a 2016 study of rats ( found that rosmarinic acid enhances the long-term potentiation of BDNF and “can even enhance neural plasticity.”

Medicine Man’s The Brain Pill stands out because, rather than merely temporarily boosting your brain power, it naturally supports the brain to improve cognitive function and maintain mental sharpness over long periods. 

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Woman taking supplements.

Supplements for brain fog after COVID:

Let the brain help itself


When looking to combat the deleterious effects of COVID-19 and its wide-reaching effects on cognitive health, it is paramount that you focus on improving your brain’s natural functions. COVID attacks the brain in a variety of ways, making symptoms of brain fog and other mental difficulties quite difficult to trace etiologically. Therefore, addressing the problem at the root by improving your body’s natural neural processes should be a priority. If you’re looking to clear away the clouds, look for supplements that may support brain function and overall brain health for a brighter, clearer mind.

Further Reading for Additional Reference:

Harvard Health Publishing: What is COVID-19 brain fog – and how can you clear it?

NBC News: Brain fog, other long Covid symptoms can last more than a year, study finds

The Atlantic: One of Long COVID’s Worst Symptoms Is Also Its Most Misunderstood

Columbia University Irving Medical Center: Even Mild Cases Can Cause “COVID-19 Fog”

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Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.

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