Nootropics are supplements that may improve brain function and they are becoming more and more well-liked by people of all ages. Among the many nootropics on the market, oxiracetam is a well-known substance that is praised for its capacity to improve cognition. It is a nootropic that belongs to the racetam family and is well-known for enhancing learning, memory, and cognitive function. In-depth information about Oxiracetam, including its nature, health advantages, recommended dosage, negative effects, possible drug interactions, and responsible usage will be provided on this page.
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Oxiracetam: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information is an original (NootropicsPlanet) article.
Nature of Oxiracetam
Oxiracetam is initially created by an Italian pharmaceutical company in the 1970s. It is a Piracetam derivative and a member of the racetam family of nootropics. Oxiracetam functions similarly to other racetams by altering the brain’s neurotransmitter system, particularly the acetylcholine system. It increases acetylcholine receptor activation, which boosts cognitive function.
Oxiracetam has the chemical formula C6H10N2O3 and a molecular weight of 158.155 g/mol. It is a white, crystalline powder that dissolves in water with a harsh flavor. In most cases, you can get it as powder or capsules.
Health Benefits of Oxiracetam
In-depth research has been done on oxiracetam’s capacity to improve cognitive function. It has been shown to increase learning capacity, memory, and attention span. It has additionally been discovered to possess neuroprotective qualities, making it a potential cure for neurodegenerative illnesses. The following shows how oxiracetam can make a difference in your cognitive abilities:
Improved Learning and Memory Capacity
Both short-term and long-term memory have been shown to be enhanced by oxiracetam. Oxiracetam enhanced memory retrieval and consolidation, according to research done on rats. It has also been demonstrated to improve learning capacity by increasing cognitive flexibility and attention span.
Brain-Protective Qualities
It has been discovered that oxiracetam has neuroprotective qualities. It has been demonstrated to enhance cerebral blood flow and shield neurons from oxidative stress-related damage. Aside from this, it has also been demonstrated to enhance the synthesis of nerve growth factor, a protein that supports neuronal growth and survival.
Possibility of Treating Neurodegenerative Disorders
It has been investigated whether oxiracetam can be used to treat neurodegenerative conditions like Alzheimer’s disease. Oxiracetam was proven to enhance cognitive function and lessen brain cell damage in mice with Alzheimer’s disease.
Chemistry of Oxiracetam
As mentioned, oxiracetam is part of the racetam family of substances. It is a pyrrolidone-nucleated derivative of the neurotransmitter GABA (gamma-aminobutyric acid). Despite sharing a structural similarity with piracetam and aniracetam, oxiracetam has a stronger impact on cognitive performance than other racetams.
Physiological Mechanisms of Action of Oxiracetam
However, the precise mode of action of oxiracetam is not entirely understood. The main mechanism of it is thought to increase the brain’s acetylcholine release. A neurotransmitter called acetylcholine is important in memory, learning, and attention, among other cognitive functions. As mentioned, oxiracetam may improve cognitive performance by raising acetylcholine levels.
Additionally, glutamate receptors in the brain, which are important for memory and learning processes, may become more active as a result of oxiracetam. The cognitive and memory functions of oxiracetam may be enhanced by boosting glutamate receptor activation.
It has been demonstrated that oxiracetam has neuroprotective qualities in addition to its effects on neurotransmitters. It may aid in preventing neuronal damage and offering defense against oxidative stress.
Although the precise methods by which Oxiracetam works are not entirely understood, it is thought to increase the brain’s acetylcholine release. Acetylcholine is important in memory, learning, and attention, among other cognitive functions. Oxiracetam may improve cognitive performance by raising acetylcholine levels.
Additionally, glutamate receptors in the brain, which are important for memory and learning processes, may become more active as a result of oxiracetam. The cognitive and memory functions of Oxiracetam may be enhanced by boosting glutamate receptor activation.
It has been demonstrated that Oxiracetam has neuroprotective qualities in addition to its effects on neurotransmitters. It may aid in preventing neuronal damage and offering defense against oxidative stress, which is thought to contribute to the emergence of neurodegenerative illnesses including Alzheimer’s and Parkinson’s.
Optimal Dosage of Oxiracetam
The ideal Oxiracetam dosage depends on the person’s weight, age, and general health. Adults should take between 1,200 mg and 2,400 mg per day, split into two or three doses. It is advised to begin with a lesser dose and raise it gradually over time.
Side Effects of Oxiracetam
When taken as directed, oxiracetam is usually regarded as safe. However, it can have adverse effects, especially if taken in excess, as other nootropics do. Headaches, wooziness, nausea, and insomnia are some of the most frequent side effects of oxiracetam. Most of the time, these side effects are minor and disappear on their own. Rarely, more serious side effects like seizures and allergic reactions might be brought on by oxiracetam. It’s crucial to get medical help right away if any serious adverse effects manifest.
Potential Substance Interactions with Oxiracetam
Some substances, particularly other nootropics and medicines, can interact with oxiracetam. Before using oxiracetam with any other medications, it is crucial to speak with a medical practitioner. The following are some drugs that may interact with oxiracetam:
1. Other Nootropics: Combining oxiracetam with other nootropics, especially other racetams, may lead to serious negative effects.
2. Anticoagulants: When used with anticoagulants like warfarin, oxiracetam may raise the risk of bleeding.
3. Antiplatelet medications: When taken with antiplatelet medications like aspirin, oxiracetam may raise the risk of bleeding.
4. CNS Depressants: Oxiracetam may make CNS depressants like alcohol and benzodiazepines more sedating.
Responsible Use of Oxiracetam
Utilizing oxiracetam properly is essential to prevent any possible negative effects. Following are some guidelines for using oxiracetam sensibly:
1. Take the prescribed amount: It’s crucial to take the prescribed amount and not more. It is advised to start with a smaller dose and gradually increase it over time.
2. Take pauses: To prevent any potential tolerance or reliance, it’s necessary to take breaks from oxiracetam.
3. Speak with a medical professional: It’s crucial to speak with a doctor before using oxiracetam, especially if you’re already on any other medications.
4. Oxiracetam should be stored correctly, away from direct sunlight, in a cool, dry environment.
Oxiracetam:
Conclusion
Supplements that come from the racetam family are in a group of nootropics that are believed to enhance your brain function. If you are looking to strengthen your cognitive ability, you may wish to look into oxiracetam. As introduced, oxiracetam is from the racetam family of supplements and it can alter your brain’s neurotransmitter system. To conclude its function briefly, oxiracetam can improve your memory capacity and also support neuronal growth and survival.
The structure of oxiracetam resembles one of the nucleated derivatives of neurotransmitters and thereby can cause significant brain improvement. It is also good to note that oxiracetam can exert a stronger impact than other supplements from the racetam family such as piracetam and aniracetam. You should look closely into your specific needs for cognitive advancement and seek professional advice before beginning an oxiracetam supplementation routine.
References:
- Zhang, H., Jia, L., & Jia, J. (2020). Oxiracetam offers neuroprotection by reducing amyloid Β-Induced microglial activation and inflammation in Alzheimer’s disease. Retrieved from: Frontiers in Neurology, 11.
- Wang, D., Wei, Y., Tian, J., He, D., Zhang, R., Ji, X., Huang, X., Sun, J., Gao, J., Wang, Z., Pang, Q., & Liu, Q. (2021). Oxiracetam mediates neuroprotection through the regulation of microglia under Hypoxia-Ischemia neonatal brain injury in mice. Retrieved from: Molecular Neurobiology, 58(8), 3918–3937.
- Niu, F., Sharma, A., Wang, Z., Feng, L., Mureşanu, D. F., Sahib, S., Tian, Z. R., Lafuente, J. V., Buzoianu, A. D., Castellani, R. J., Nozari, A., Menon, P., Patnaik, R., Wiklund, L., & Sharma, H. S. (2021). Nanodelivery of oxiracetam enhances memory, functional recovery and induces neuroprotection following concussive head injury. Retrieved from: In Progress in brain research (pp. 139–230).
Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.
Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.
