Chenopodium Oil: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information


Share post:

- Advertisement -

There are now a plethora of natural supplement options available, many of which aim to enhance general health, physical performance, and mental well-being. The focus on plant-based sources has led to the introduction of a variety of oils with noteworthy health advantages among these varied products. Chenopodium oil, which is made from the seeds of the Chenopodium plant, is one of these oils that has gained notice recently.

You May Also Like:

Citronella Oil: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information

Cod Liver Oil: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information

Chenopodium Oil: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information is an original (NootropicsPlanet) article.

The Nature of Chenopodium Oil

Chenopodium ambrosioides and Chenopodium anthelminticum are the two main species from which Chenopodium oil, sometimes called Epazote oil or wormseed oil, is obtained. This oil has an amber tint and contains several phytochemicals, the most important of which is ascaridole. The main bioactive component of Chenopodium oil is ascaridole, a bicyclic monoterpene peroxide that makes up between 60 and 80 percent of its makeup.

- Advertisement -

Health Benefits of Chenopodium Oil

The powerful anthelmintic (anti-parasitic) characteristics of Chenopodium oil are principally responsible for the oil’s beneficial effects on health. The main active ingredient, ascaridole, has substantial anti-intestinal parasite action. This is mainly because of its capacity to change the permeability of parasite cell membranes, which ultimately results in their demise and evacuation from the host.

Additionally, early research points to the possibility of ascaridole’s anti-cancer effects. Studies conducted in the lab have shown that it causes apoptosis, or programmed cell death, in a number of cancer cell lines by interfering with mitochondrial activity

Furthermore, gastrointestinal problems including bloating and stomach cramps are usually treated with chenopodium oil. The antispasmodic effects of ascaridole aid to calm the smooth muscles of the stomach, preventing spasms, and enhancing digestion.

Dead cell.

Chemistry of Chenopodium Oil

The bioactive substance ascaridole is at the heart of Chenopodium oil’s chemical makeup. As previously stated, ascaridole is a chemical compound with two fused rings and a peroxide group which is also known as bicyclic monoterpene peroxide. 

The peroxide renders ascaridole extremely reactive, which is essential to its biological activity since it is an unstable group. The oil also includes p-cymene, limonene, and -terpinene, albeit their quantities and biological effects are less evident than those of ascaridole.

Physiological Mechanisms of Action of Chenopodium Oil

The major component of Chenopodium oil, ascaridole, has a fascinating and complex physiological mechanism of action. The oil works by upsetting the biological processes of parasites due to its anthelmintic qualities.

A crucial component of ascaridole’s anti-parasitic action is the peroxide group. In the parasitic organism, the unstable peroxide bond breaks after feeding, generating reactive oxygen species (ROS). These ROS lead to oxidative stress, which weakens vital processes and harms cellular structures.

In particular, when the integrity of the cell membrane is weakened, its permeability will increase.  This throws off the parasite’s internal balance, leading to its eventual death and ejection from the host body.

- Advertisement -

Optimal Dosage of Chenopodium Oil

Due to its strength and potential for side effects, figuring out the ideal dose for Chenopodium oil may be difficult. Nevertheless, based on historical use and little scientific evidence, a typical dosage for anthelmintic purposes may be as little as 2 to 3 drops of oil given orally once a day. Due to the possibility of adverse consequences and drug interactions, this should always be carried out under the supervision of a healthcare professional.

Side Effects of Chenopodium Oil

Although Chenopodium oil has many health advantages, it may also have negative consequences due to its neurotoxic qualities. In extreme circumstances, ascaridole may cause convulsions or loss of consciousness in addition to symptoms including headaches, nausea, vomiting, and dizziness when taken in large dosages. Furthermore, when used topically, the oil might irritate the skin or trigger allergic responses. Therefore, it is essential to begin with small dosages and monitor the body’s response before increasing consumption.

A girl having vomit.

Potential Substance Interactions with Chenopodium Oil

The potential neurotoxic effects of chenopodium oil make it possible for it to interact with certain drugs, especially those that influence the central nervous system. As a result, anyone utilizing sedatives, antiepileptic medicines, or other neurologically active treatments should take extra care and attention when using this oil.

Theoretically, the oil’s possible antispasmodic effects may also interact with medicines that impact smooth muscles, including antihypertensives or IBS-management therapies. Before beginning any new supplement regimen, you should always speak with a healthcare professional.

Professional healthcare.

The Responsible Use of Chenopodium Oil

It is essential that Chenopodium oil be used carefully due to the possible negative effects and interactions. This also implies beginning with a modest dosage, ideally with a healthcare provider’s supervision. It’s also crucial to pay attention to your health and stop using it if any negative side effects appear.

In conclusion, Chenopodium oil may be beneficial for your health due to its high ascaridole concentration and possible anthelmintic, anticancer, and antispasmodic effects. These advantages must be contrasted with any negative effects or interactions, however. Future studies will help define the oil’s function as a nutritional supplement by determining its specific mechanisms of action, the ideal dose, and its long-term safety.

- Advertisement -

Chenopodium Oil:


In conclusion, Chenopodium oil, extracted from the seeds of the Chenopodium plant, offers unique benefits if you are seeking natural wellness solutions for your gut health. With its rich composition of bioactive compounds, Chenopodium oil has been recognized for its potential health-promoting properties for gastrointestinal problems such as anthelmintic properties and antispasmodic effects. This oil holds an active ingredient known as ascaridole that can effectively prevent parasite action in the intestinal tract.

Ascaridole also contributes to the anti-cancer properties of this oil. When considering adding Chenopodium oil to your new supplement regimen, it is recommended that you seek professional advice from doctors and buy from trusted sources to ensure your safety. By making informed choices and seeking guidance, you can explore the potential benefits of Chenopodium oil and use it wisely to improve your overall health and wellness.


  1. Essential Oils and Their Constituents: An Alternative Source for Novel Antidepressants. Retrieved from:
  2. Chenopodium Oil – Uses, Side Effects, and More.Retrieved from:
  3. Chenopodium ambrosioides L. Reduces Synovial Inflammation and Pain in Experimental Osteoarthritis. Retrieved from:

Important Note: The information contained in this article is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

Regarding Nutritional Supplements Or Other Non-Prescription Health Products: If any nutritional supplements or other non-prescription health products are mentioned in the foregoing article, any claims or statements made about them have not been evaluated by the U.S. Food and Drug Administration, and such nutritional supplements or other health products are not intended to diagnose, treat, cure, or prevent any disease.

Related articles

APPLE: Benefits, Dosage, Side Effects, Drug Interactions, And Other Important Information

One of the most well-liked and extensively consumed fruits worldwide is the apple. Apples include a wealth of...

APPLE CIDER VINEGAR: Benefits, Dosage, Side Effects, Drug Interactions, And Other Important Information

The use of apple cider vinegar (ACV) for flavouring, food preservation, and medical applications dates back hundreds of...

BA JI TIAN: Benefits, Dosage, Side Effects, Drug Interactions, And Other Important Information

Popular dietary supplement BA JI TIAN is frequently used to improve general health and wellness. This natural supplement...

Vitamin D: Benefits, Dosage, Side Effects, Drug Interactions, and Other Important Information

Vitamin D, often referred to as the "sunshine vitamin," plays a crucial role in the human body's functioning,...